| 학회지 검색 | HOME > 논문 및 학회지 > 학회지 검색 |
대한생식의학회지 제29권 제2호 2010년
심한 무력정자증 환자의 ICSI 시행시 Pentoxifylline을 사용한 정자처리법이 임상결과에 미치는 영향
차병원 여성의학연구소1, 포천 중문의과대학2
손지온, 신지수1,정창진1,2,조용선1,2,엄기붕1,2,최동희1,2,김현주1,2
Effect of Pentoxifylline on the ICSI Program Undergone in Severe Asthenozoospermia
JO Sohn
Infertility Medical Center, CHA General Hospital of Seoul1, Pochon CHA University
Objective: The aim of this study was to evaluate the effect of pentoxifylline (PF) on the conventional ICSI program undergone in severe asthenozoospermia. Method: Total 348 cycles of ICSI programs undertaken at CHA General Hospital from January, 1996 to September, 2000, were divided into two groups - injected with pentoxifylline-treated sperm (PFT, 204 cycles) or non-treated sperm (NPFT, 144 cycles) and the clinical results of PFT group were compared with those of NPFT. Results: PF-treatment on sperm increased their motility of normozoospermia and severe asthenozoospermia. Fertilization rate of PFT group was higher than those of ICSI programs undertaken using sperm of NPFT (70.6% vs. 62.9%, p<0.01). And, ET and clinical pregnancy rates of PFT were slightly higher than those of NPFT (93.1%, 44.2% vs. 90.3%, 36.2%). Conclusion: These results showed that treatment of pentoxifylline has a beneficial role on selection of viable sperm in severe asthenozoospermia.
키워드 : Pentoxifylline, Asthenozoospermia, ICSI
교신저자 :
전문 파일 : 
