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대한생식의학회지 제30권 제2호 2010년
만성 골수성 백혈병과 재생 불량성 빈혈로 진단받은 환자의 치료 전 동결보존된 정자를 이용한 세포질내 정자주입술로 임신에 성공한 2례
포천중문 의과대학 산부인과학교실, 비뇨기과학교실, 불임의학연구실, 가톨릭대학교 의과대학 내과학교실
한지은, 정태규,정미경,민우성,이숙환,윤태기
Successful Pregnancy by ICSI using Spermatozoa Banked Prior to Bone Marrow Transplantation for Severe Apalstic Anemia and Chronic Myelogenous Leukemia
Jee Eun Han
Department of Ob&Gy, Department of Urology, Infertility Medical Center, CHA General Hospital, Department of Internal Medicine, College of Medicine, Catholic University, Seoul Korea
Objective: To report tow cases of successful pregnancies following long term cryopreserved spermatozoa prior to bone marrow transplantation (BMT) for chronic myelogenous leukemia (CML) and severe aplastic anemia (SAA). Materials and Methods: Case report. Results: With the first case, after cryopreservation of semen from 25 year-old man with CML prior to BMT, his wife is being pregnant by intracytoplasmic sperm injection (ICSI) using thawed spermatozoa. With the second case, 28 year-old man with SAA became father by ICSI using banked spermatozoa before BMT. Conclusion: These cases support that men with malignancy have the chance of fathering their own genetic children. It is important therefore, to increase the awareness of clinicians especially oncologists and patients themselves to the new developments in preserving fertility for cancer patients.
키워드 : Semen cryopreservation, ART, ICSI, CML, SAA
교신저자 : dnalee@nuri.net
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