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대한생식의학회지 제32권 제4호 2010년
남성호르몬 투여 받은 성 주체성 장애 환자에서 적출된 자궁 및 부속기의 조직학적 특징에 관한 고찰
동아대학교 의과대학 산부인과학교실, 해부병리학교실1, 성형외과학교실2*
변재천,, 곽봉규,신지현,차문석,한명석,나서희1,김석권2*
The Histologic Features of the Uterus and Adnexa Extirpated from Gender Identity Disorder Patients with Depot Androgen Injection
Jae Chun Byun, Bong Gyu Kwak, Ji Hyun Shin, Moon Seok Cha, Myoung Seok Han, Seo Hee Rha1, Seok Kwun Kim2*
Department of Obstetrics and Gynecology, 1Department of Pathology, 2*Department of Plastic Surgery, College of Medicine, Dong-A University, Busan, Korea
.
Objective: To investigate the histologic features of the uterus and adnexae extirpated from gender identity disorder (GID) patients that received depot androgen injection. Methods: We reviewed the histologic findings of the uterus and adnexae removed from sixteen GID patients, who had taken depot androgen injection for 5~168 months. Results: Fourteen patients (87.5%) showed the atrophied epithelium of exocervix and all of 16 patients (100%) showed the atrophy of endometrium. Seven patients (43.7%) showed multiple cystic follicles in the ovarian cortex and 6 patients (37.5%), 3 patients (18.7%) showed corpus albicans and corpus luteum, respectively. Conclusions: Exogenous androgen induced atrophy of cervix and endometrium. This effect was more prominent in the endometrium. In addition, PCO-like histologic features were observed in the ovary.
키워드 : Gender identity disorder (GID), Androgen therapy, Atrophy
교신저자 : chamchi@naver.com
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