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대한생식의학회지 제15권 제1호 2010년
여성 생삭기에 있어서의 ${\beta}$-Endorphin에 관한 면역조직학적 연구
서울대학교 의과대학 산부인과학교실;서울대학교 의과대학 산부인과학교실;서울대학교 의과대학 산부인과학교실;서울대학교 의과대학 산부인과학교실;서울대학교 의과대학 산부인과학교실;
김정구;민응기;문신용;이진용;장윤석;,
Immunoreactive ${\beta}$-Endorphin in Female Reproductive Organs
Kim, Jung-Gu;Min, Eung-Gi;Moon, Shin-Yong;Lee, Jin-Yong;Chang, Yoon-Seok;
Department of Obstetrics and Gynecology, College of Medicine，Seoul National University;Department of Obstetrics and Gynecology, College of Medicine，Seoul National University;Department of Obstetrics and Gynecology, College of Medicine，Seoul National University;Department of Obstetrics and Gynecology, College of Medicine，Seoul National University;Department of Obstetrics and Gynecology, College of Medicine，Seoul National University;
The aim of this study was to examine the presence of ${\beta}$-endorphin in female reproductive organs. A total of 104 fresh tissue samples were obtained from normal ovary, tube, endometrium, placenta, amniotic membrane and umbilical cord, and immunostained by the method using biotin-streptoavidin amplified system. The results were as follows: 1. In reproductive age, corpus luteum only showed ${\beta}$-endorphin immunostained cells but no cells in ovaries during proliferative phase of menstrual cycle were stained. 2. Secretory endometrium revealed positive reactions in the cytoplasm of glandular epithelial cells and around the vessels, while proliferative endometrium negative reactions. 3. All the tissues of menopausal women were negative to ${\beta}$-endorphin antibody. 4. In the pregnant women, there are no ${\beta}$-endorphin containing cells in the placenta, amniotic membrane and umbilical cord regardless of gestational age.
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