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대한생식의학회지 제17권 제1호 2010년
체외수정시술시 미세조작술에 의한 수정률 향상과 임신에 관한 연구
제일병원 산부인과 체외수정 연구실;제일병원 산부인과 체외수정 연구실;제일병원 산부인과 체외수정 연구실;제일병원 산부인과 체외수정 연구실;제일병원 산부인과 체외수정 연구실;한양대학교 자연과학대학 생물학과;
이호준;최규완;전종영;박종민;권혁찬;김문규;,
Study on Pregnancy and Improvement of Fertilization rate by Micromanipulation (Partial Zona Dissection (PZD) and Micro-Insemination by Sperm Transfer(MIST) in human IVF-ET
Lee, Ho-Joon;Choi, Kyoo-Wan;Jun, Jong-Yung;Park, Jong-Min;Kwon, Hyuck-Chan;Kim, Moon-Kyoo;
IVF Research Laboratory, Department of Obstetrics and Gynecology, Cheil General Hospital;IVF Research Laboratory, Department of Obstetrics and Gynecology, Cheil General Hospital;IVF Research Laboratory, Department of Obstetrics and Gynecology, Cheil General Hospital;IVF Research Laboratory, Department of Obstetrics and Gynecology, Cheil General Hospital;IVF Research Laboratory, Department of Obstetrics and Gynecology, Cheil General Hospital;Department of Biology, College of Natural Science, Hanyang University;
The purpose of this study is to improve fertilization rate in IVF-ET program of patients with male infertility used micromanipulation technique, partial zona dissection (PZD) or micro-insemination by sperm transfer (MIST). The results were as follows 1. The fertilization rate of non-micromanipulated oocytes and micromanipulated (PZD) oocytes were 12.5% (n=2) and 42.2% (n=19), respectively, and showed significant differences between two groups (p<0.05). 2. The fertilization rate of micromanipulated (MIST) oocytes was 30% (n=27). 3. The damage rate of Group 1 (PZD) and Group 2 (MIST) were 15.7% (3/19) and 29.6% (8/27), respectively. 4. One pregnancy resulted following replacement of micromanipulated (MIST) embryos in 4 patients.
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