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대한생식의학회지 제25권 제2호 2010년
원형정자세포의 주입에 의한 임신과 분만 1례
하나병원 불임연구실, 대구대학교 공과대학, 건국대학교 축산대학
이상민, 정지영, 한용태, 박해택, 박흠대, 정길생, 이기영,
Pregnancy and Delivery by Round Spermatid Injection into Oocytes in Human
Lee sm, Jung jy, Han yt, Park ht, Park hd, Chung ks, Lee ky
We demonstrated that the normal pregnancy and delivery by round spermatid injection(ROSI) into oocytes was achieved from nonobstructive azoospermia patient. In this case, the normal fertilization rate was 50%. All of the two-pronuclear stage embryos cleaved and were transferred to the patient’s uterus. A singleton pregnancy was achieved and resulted in the birth of normal female infant. This result show that intracytoplasmic injection of round spermatid seems to be new treatment of nonobstructive azoospermia male infertility. Further research is needed to evaluate the required culture conditions to induce progression of the round spermatid into a more elongated stage.
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