| 학회지 검색 | HOME > 논문 및 학회지 > 학회지 검색 |
대한생식의학회지 제26권 제1호 2010년
Tumor necrosis factor-alpha가 정자운동성에 미치는 직접 영향의 부족
인하대학교 의과대학 산부인과학교실
송은섭, 임영구,
The Lack of a Direct Effect of Tumor Necrosis Factor-Alpha on Sperm Motility
Song es, Lim yk
Male genital tract inflammatory conditions may be associated with unexplained infertility. The presence of cytokine such as tumor necrosis factor-alpha (TNF-α) was reported in the semen of infertile men. However, the effect of these cytokines on human sperm function is still unclear. The purpose of this study was to investigate the in-vitro effects of TNF-alpha on human sperm motility with computer assisted sperm analysis. Washed sperm from 16 normal men were incubated without and with TNF-α (0.1, 10, 1000ng/ml). The changes of parameters of sperm motility were recorded at different time intervals (0, 5, 24 hour). There was no significant change of parameters of sperm motility in the incubation with TNF-α. It is suggested that TNF-α alone does not interfere with the sperm motility and more studies are needed.
키워드 : Tumor necrosis factor-alpha, Sperm motility
교신저자 :
전문 파일 : 
